Principal Investigator

Priya Vashisth

Assistant Professor, Center for Biomedical Engineering-

Dr. Priya Vashisth joined the Centre for Biomedical Engineering at IIT Delhi as an Assistant Professor in 2023. Her research focus includes the development of biomedical implants and localized drug delivery systems to treat complex coronary vascular diseases. Dr. Vashisth is also enthusiastic about creating tissue-based Exvivo platforms to understand vascular pathophysiology and to evaluate the effect of various therapies and interventions. Such systems can reduce the dependency on animal models. She obtained a Ph.D. degree in Biotechnology from IIT Roorkee in 2016, where she developed microbial polysaccharides-based dermal grafts using an electrospinning technique. She was a postdoctoral research associate at King’s College London where she explored nano-needles-based platforms for localized drug and gene therapies. She also has served IIT Delhi as a DST-Inspire Faculty and developed bioresorbable and biostable drug-eluting vascular stents to treat atherosclerosis.

Email: pvashisth@iitd.ac.in

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Research Interests

Biomedical Implants
Biomaterials
Drug delivery
Tissue based EXVIVO bioreactors

Peer Reviewed Journal Publications

1. Kaustubh Naik, Shikha Tripathi, Rahul Ranjan, Somesh Agrawal, Saurabh Kr Srivastava, Prodyut Dhar, Priya Vashisth et. al., (2025) Bioactive Hyaluronic acid–Protein based amyloidogenic hydrogel dressing for rapid diabetic wound healing via enhanced angiogenesis and anti-inflammation. Materials Today Communications. 113560.
2. Sonu Singh, Jivesh Jain, Sunil Kumar Yadav, Prashant Kumar, Vijay Kumar Meena, Priya Vashisth, Dinesh Kalyanasundaram (2025). Evaluation of fatigue life of additively manufactured Ti6Al4V neovius lattices in simulated body fluid for biomedical applications. Advanced Engineering Materials. Vol 27 (7) 2402368.
3. Chantelle Spiteri, Valeria Caprettini, Yikai Wang, Sofia Dominguez‐Gil, Martti Kaasalainen, Cong Wang, Davide Alessandro Martella, Samuel McLennan, Priya Vashisth et. al., (2024). Spatially‐Resolved Organoid Transfection by Porous Silicon‐Mediated Optoporation. Advanced Materials, 2407650
4. Cong Wang, Chenlei Gu, Courtney Popp, Priya Vashisth et al., (2024) Integrating Porous Silicon Nanoneedles within Medical Devices for Nucleic Acid Nanoinjection. ACS Nano, 18, 23, 14938–14953.
5. Alok Srivastava, Pooja Bhati, Shweta Singh, Mohit Agrawal, Nisha Kumari, Priya Vashisth et.al., (2024). A review on polylactic acid‐based blends/composites and the role of compatibilizers in biomedical engineering applications. Polymer Engineering & Science. 64 (3) 1003-1044.
6. M Kaasalainen, R Zhang, P Vashisth, AA Birjandi, et al., (2024) Lithiated porous silicon nanowires stimulate periodontal regeneration. Nature Communications, 15, 1, 487.
7. A Srivastava, S Singh, P Bhati, N Kumari, M Pandya, P Vashisth, P Chauhan, N Bhatnagar. (2024) Fabrication and characterization of PLLA/PCL/Mg‐Zn‐Y alloy composite stent. Polymer Engineering & Science. 64,1 243-253.
8. S Singh, R Roy, V K Meena, P Vashisth, D Kalyanasundaram (2024). Nanotextured and drug loaded Neovius Ti6Al4V ELI scaffolds with osteogenesis and anti-cancer potential. Materials & Design, 237, 112570.
9. Sonu Singh, Sunil Kumar Yadav, Vijay Kumar Meena, Priya Vashisth, Dinesh Kalyanasundaram (2023). Orthopedic scaffolds: evaluation of structural strength and permeability of fluid flow via an open cell neovius structure for bone tissue engineering. ACS Biomaterials Science & Engineering. Vol 9(10) 5900-5911
10. Pooja Bhati, Alok Srivastava, Ramya Ahuja, Pankaj Chauhan, Priya Vashisth, Naresh Bhatnagar (2023). Physicochemical properties of UV-irradiated, biaxially oriented PLA tubular scaffolds. Polymers. Vol 15(5) 1097
11. S Singh, P Vashisth, VK Meena, D Kalyanasundaram (2022). Cellular studies and sustained drug delivery via nanostructures fabricated on 3D-printed porous Neovius lattices of Ti6Al4V ELI. Biomedical Materials 17, (4) 045004.
12. D Gupta, P Vashisth, J Bellare (2021). Multiscale porosity in a 3d printed gellan–gelatin composite for bone tissue engineering. Biomedical Materials 16 (3), 034103.
13. P Vashisth, N Kar, D Gupta, JR Bellare (2020). Three Dimensional Quercetin-Functionalized Patterned Scaffold: Development, Characterization, and In Vitro Assessment for Neural Tissue Engineering ACS omega 5 (35), 22325-22334.
14. P Bhati, R Ahuja, A Srivastava, S Singh, P Vashisth, N Bhatnagar (2020). Physicochemical characterization and mechanical performance analysis of biaxially oriented PLA/PCL tubular scaffolds for intended stent application. SN Applied Sciences 2 (12), 1-11.
15. R Ahuja, A Kumar, A Srivastava, P Bhati, P Vashisth, N Bhatnagar (2020). Biocompatibility Analysis of PLA based Candidate Materials for Cardiovascular Stents in a Rat Subcutaneous Implant Model, Acta Histochemica 122 (7), 151615.
16. A Srivastava, R Ahuja, P Bhati, S Singh, P Chauhan, P Vashisth, A Kumar, N Bhatnagar (2020). Fabrication and Characterization of PLLA/Mg Composite Tube as the potential Bioresorbable/biodegradable stent (BRS). Materialia. Volume 10, May 2020, 100661.
17. S Singh, P Vashisth, A Shrivastav, N Bhatnagar (2019). Synthesis and characterization of a novel open cellular Mg-based scaffold for tissue engineering application. Journal of the Mechanical Behaviour of Biomedical Material. Volume 94, 54-62.
18. P Vashisth & J Bellare (2018). Development of Hybrid Scaffold with Biomimetic 3D Architecture for Bone Regeneration. Nanomedicine -Nanotechnology Biology and Medicine. Volume 14 (4), 1325-1336.
19. N Raghuwanshi, AK Srivastava, P Vashisth, R Prasad & V Pruthi (2017). Synergistic effects of Woodfordia fruticosa gold nanoparticles in preventing microbial adhesion and accelerating wound healing in Wistar albino rats in vivo. Materials Science & Engineering C. Volume 80, 252 262.
20. P Vashisth, A Srivastava, H Nagar, N Raghuvanshi, S Sharan, P Roy, RP Singh, V Pruthi (2016). Drug functionalized microbial polysaccharide based nanofibers as transdermal substitute. Nanomedicine -Nanotechnology Biology and Medicine. Volume 12, 1375-1385.
21. P Vashisth, N Raghuvanshi, H Nagar, AK Srivastava, RP Singh, V Pruthi (2016). Ofloxacin Loaded Gellan/PVA Nanofibers - Synthesis, Characterization and Evaluation of their Gastroretentive/ Mucoadhesive Drug Delivery Potential. Materials Science and Engineering C. Volume 71, 611-619.
22. P Vashisth & V Pruthi (2016). Synthesis and characterization of crosslinked gellan/PVA nanofibers for tissue engineering applications. Materials Science & Engineering C. Volume 67, 304-312.
23. P Vashisth, K Nikhil, P Roy, RP Singh, V Pruthi (2016). A novel gellan–PVA nanofibrous scaffold for skin tissue regeneration: Fabrication and characterization. Carbohydrate Polymers. Volume 136, 851-859.
24. P Vashisth, RP Singh, V Pruthi (2015). A controlled release system for quercetin from biodegradable PLGA-PCL nanofibers and it’s in vitro antitumor activity. Journal of Bioactive and Compatible Polymers. 31,3,1-13.
25. P Vashisth, N Kumar, M Sharma, V Pruthi (2015). Biomedical applications of ferulic acid encapsulated electrospun nanofibers. Biotechnology Reports, Volume 8, 36–44.
26. P Vashisth, M Sharma, K Nikhil, H Singh, R Panwar, PA Pruthi, RP Singh, V Pruthi (2015). Antiproliferative activity of ferulic acid encapsulated electrospun PLGA/PEO nanofibers against MCF-7 human breast carcinoma cells. 3 Biotech, Volume 5: 303–315.
27. P Vashisth, PA Pruthi, RP Singh & V Pruthi (2014). Process optimization for fabrication of gellan based electrospun nanofibers. Carbohydrate Polymers, Volume 109, 16-21.
28. P Vashisth, K Nikhil, SC Pemmaraju, PA Pruthi, H Singh, A Patel, NC Mishra, RP Singh & V Pruthi (2013). Antibiofilm activity of quercetin-encapsulated cytocompatible nanofibers against Candida albicans. Journal of Bioactive and Compatible Polymers, Volume 28(6), 652–665.
29. P Vashisth, H Singh, PA Pruthi, RP Singh & V Pruthi (2014). Evaluation of gellan based electrospun nanofibers for wound healing. Nanocon-2014 Conference Proceedings, 514-518.
30. N Raghuwanshi, A Pathak, A Patel, P Vashisth, H Singh, AK Srivastava, V Pruthi (2017). Novel biogenic synthesis of silver nanoparticles and their therapeutic potential. Frontiers in Bioscience, Elite, Volume 9, 33-43.
31. SA. Wadhwani, U. Shedbalkar, R Singh, P Vashisth, V Pruthi & B A. Chopade (2016). Kinetics of synthesis of gold nanoparticles by acinetobacter sp. sw30 isolated from environment. Indian Journal of Microbiology, Volume 53, 439-444.
32. Kaushik Ghosh, Sweety Rathi, Pankaj Gupta, Priya Vashisth & Vikas Pruthi (2015). A simple fluorescent probe derived from naphthylamine for selective detection of Hg(II), Fe(II), Fe(III) ions in mixed aqueous media: Applications in living cells and logic gates. European J of Inorganic Chemistry, Volume (2)311-317.
33. GR Salunke, S Ghosh, S Khade, P Vashisth, T Kale, V Pruthi, G Kundu, JR Bellare, BA Chopade (2014). Rapid efficient synthesis and characterization of AgNPs, AuNPs and AgAuNPs from a medicinal plant, Plumbago zeylanica and their application in biofilm control. International Journal of Nanomedicine, Volume 9(1) 2635–2653.

Education

Doctor of Philosophy
"Designing of gellan based electrospun nanofibers for biomedical applications", (2011- 2016), Department of Biotechnology, Indian Institute of Technology Roorkee, India

Professional Experience

Assistant Professor, Centre for Biomedical Engineering, Indian Institute of Technology Delhi, India (Jun,2023 - Present)
DST-INSPIRE Faculty, Department of Mechanical Engineering, Indian Institute of Technology Delhi, India(Oct, 2018 - Jun 2023)
Research Scientist, King's College London, UK(Oct, 2021 - May, 2023)
Postdoctoral Fellow, Indian Institute of Technology Bombay, India (Jul,2016 - Jun,2018)

Awards & Honors